Deletion of tetraspanin CD151 alters the Wnt oncogene-induced mammary tumorigenesis: A cell type-linked function and signaling

Tetraspanin CD151 is increasingly implicated as a multifaceted mediator of cancer development and progression. Here we investigated the role of CD151 in breast cancer in the context of the Wnt oncogenic activation. Our data showed that removal of one or both of CD151 alleles in the MMTV-Wnt1 model s...

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Bibliographic Details
Main Authors: Hongxia Li, Jieming Li, Rongbo Han, Xinyu Deng, Junfong Shi, Huanhuan Huang, Nevean Hamad, Abigail McCaughley, Jinpeng Liu, Chi Wang, Kuey Chen, Dongping Wei, Jun Qiang, Sean Thatcher, Yadi Wu, Chunming Liu, Olivier Thibault, Xiaowei Wei, Song Chen, Hai Qian, Binhua P. Zhou, Pao Xu, Xiuwei H. Yang
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558619302787