Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens.

Development of novel monoclonal antibodies with specific binding affinity for denatured human CD26 in formalin-fixed paraffin-embedded and decalcified specimens.

A 110-kDa type II transmembrane glycoprotein with dipeptidyl peptidase IV (DPPIV) activity in its extracellular region, CD26 has a multitude of biological functions and plays an important role in the regulation of inflammatory responses and tumor biology. Our work has focused on CD26 as a novel ther...

Full description

Bibliographic Details
Main Authors: Ryo Hatano, Taketo Yamada, Hiroko Madokoro, Haruna Otsuka, Eriko Komiya, Takumi Itoh, Yuka Narita, Satoshi Iwata, Hiroto Yamazaki, Shuji Matsuoka, Nam H Dang, Kei Ohnuma, Chikao Morimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0218330

Internet

https://doi.org/10.1371/journal.pone.0218330

Similar Items