Rif1 Controls DNA Replication Timing in Yeast through the PP1 Phosphatase Glc7
The Rif1 protein, originally identified as a telomere-binding factor in yeast, has recently been implicated in DNA replication control from yeast to metazoans. Here, we show that budding yeast Rif1 protein inhibits activation of prereplication complexes (pre-RCs). This inhibitory function requires t...
Main Authors: | Stefano Mattarocci, Maksym Shyian, Laure Lemmens, Pascal Damay, Dogus Murat Altintas, Tianlai Shi, Clinton R. Bartholomew, Nicolas H. Thomä, Christopher F.J. Hardy, David Shore |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-04-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714001880 |
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