ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins

ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins

Previous studies in nonhuman primates revealed a striking positive correlation between liver cholesteryl ester (CE) secretion rate and the development of coronary artery atherosclerosis. CE incorporated into hepatic VLDL is necessarily synthesized by ACAT2, the cholesterol-esterifying enzyme in hepa...

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Bibliographic Details
Main Authors: Ryan E. Temel, Li Hou, Lawrence L. Rudel, Gregory S. Shelness
Format: Article
Language:English
Published: Elsevier 2007-07-01
Series:Journal of Lipid Research
Subjects:
atherosclerosis
lipid mobilization
lipoprotein assembly
very low density lipoprotein
apolipoprotein B
triglycerides
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520425465

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http://www.sciencedirect.com/science/article/pii/S0022227520425465

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