ACAT2 stimulates cholesteryl ester secretion in apoB-containing lipoproteins
Previous studies in nonhuman primates revealed a striking positive correlation between liver cholesteryl ester (CE) secretion rate and the development of coronary artery atherosclerosis. CE incorporated into hepatic VLDL is necessarily synthesized by ACAT2, the cholesterol-esterifying enzyme in hepa...
Main Authors: | Ryan E. Temel, Li Hou, Lawrence L. Rudel, Gregory S. Shelness |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2007-07-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520425465 |
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