OxymaPure/DIC: An Efficient Reagent for the Synthesis of a Novel Series of 4-[2-(2-Acetylaminophenyl)-2-oxo-acetylamino] Benzoyl Amino Acid Ester Derivatives

OxymaPure (ethyl 2-cyano-2-(hydroxyimino)acetate) was tested as an additive for use in the carbodiimide (DIC) approach for the synthesis of a novel series of α-ketoamide derivatives (4-[2-(2-acetylaminophenyl)-2-oxo-acetylamino]benzoyl amino acid ester derivatives). OxymaPure showed clear superior...

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Bibliographic Details
Main Authors: Ayman El-Faham, Zainab Al Marhoon, Ahmed Abdel-Megeed, Fernando Albericio
Format: Article
Language:English
Published: MDPI AG 2013-11-01
Series:Molecules
Subjects:
DIC
Online Access:http://www.mdpi.com/1420-3049/18/12/14747