Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells.

Distinctive responsiveness to stromal signaling accompanies histologic grade programming of cancer cells.

Whether stromal components facilitate growth, invasion, and dissemination of cancer cells or suppress neoplastic lesions from further malignant progression is a continuing conundrum in tumor biology. Conceptualizing a dynamic picture of tumorigenesis is complicated by inter-individual heterogeneity....

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Bibliographic Details
Main Authors: Maria Gloria Luciani, Junhee Seok, Aejaz Sayeed, Stacey Champion, William H Goodson, Stefanie S Jeffrey, Wenzhong Xiao, Michael Mindrinos, Ronald W Davis, Shanaz H Dairkee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098270?pdf=render

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http://europepmc.org/articles/PMC3098270?pdf=render

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