Analysis of miRNA and mRNA expression profiles highlights alterations in ionizing radiation response of human lymphocytes under modeled microgravity.

<h4>Background</h4>Ionizing radiation (IR) can be extremely harmful for human cells since an improper DNA-damage response (DDR) to IR can contribute to carcinogenesis initiation. Perturbations in DDR pathway can originate from alteration in the functionality of the microRNA-mediated gene...

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Bibliographic Details
Main Authors: Cristina Girardi, Cristiano De Pittà, Silvia Casara, Gabriele Sales, Gerolamo Lanfranchi, Lucia Celotti, Maddalena Mognato
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22347458/?tool=EBI