BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations

<p>Abstract</p> <p>Background</p> <p>Basal-like breast cancers (BLBC) are aggressive breast cancers for which, so far, no targeted therapy is available because they typically lack expression of hormone receptors and HER2. Phenotypic features of BLBCs, such as clinical p...

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Bibliographic Details
Main Authors: van de Vijver Marc J, Børresen-Dale Anne-Lise, Langerød Anita, Velds Arno, Horlings Hugo M, Holstege Henne, Nederlof Petra M, Jonkers Jos
Format: Article
Language:English
Published: BMC 2010-11-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/10/654

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http://www.biomedcentral.com/1471-2407/10/654

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