Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells
Abstract The brain produces steroids de novo from cholesterol, so‐called “neurosteroids.” The Purkinje cell, a cerebellar neuron, was discovered as a major site of the biosynthesis of neurosteroids including sex steroids, such as progesterone, from cholesterol in the brain. Allopregnanolone, a proge...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-03-01
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Series: | FASEB BioAdvances |
Subjects: | |
Online Access: | https://doi.org/10.1096/fba.2019-00055 |