Pinning Control for the p53-Mdm2 Network Dynamics Regulated by p14ARF

Pinning Control for the p53-Mdm2 Network Dynamics Regulated by p14ARF

p53 regulates the cellular response to genotoxic damage and prevents carcinogenic events. Theoretical and experimental studies state that the p53-Mdm2 network constitutes the core module of regulatory interactions activated by cellular stress induced by a variety of signaling pathways. In this paper...

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Bibliographic Details
Main Authors: Oscar J. Suarez, Carlos J. Vega, Edgar N. Sanchez, Ana E. González-Santiago, Otoniel Rodríguez-Jorge, Alma Y. Alanis, Guanrong Chen, Esteban A. Hernandez-Vargas
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
p53
Mdm2
p14ARF
pinning control
computational modeling
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00976/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00976/full

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