Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations

Mice Deficient in Nucleoporin Nup210 Develop Peripheral T Cell Alterations

The nucleopore is an essential structure of the eukaryotic cell, regulating passage between the nucleus and cytoplasm. While individual functions of core nucleopore proteins have been identified, the role of other components, such as Nup210, are poorly defined. Here, through the use of an unbiased E...

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Bibliographic Details
Main Authors: Annemarie van Nieuwenhuijze, Oliver Burton, Pierre Lemaitre, Alice E. Denton, Ana Cascalho, Rose E. Goodchild, Bert Malengier-Devlies, Bénédicte Cauwe, Michelle A. Linterman, Stephanie Humblet-Baron, Adrian Liston
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
Nup210
CD4-positive T-lymphocytes
CD8-positive T-lymphocytes
thymus gland
spleen
nucleopore
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02234/full

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https://www.frontiersin.org/article/10.3389/fimmu.2018.02234/full

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