A Possible Link of Genetic Variations in ER/IGF1R Pathway and Risk of Melanoma

A Possible Link of Genetic Variations in ER/IGF1R Pathway and Risk of Melanoma

The mechanism of gender disparity in cutaneous melanoma incidence remains unclear. Steroid hormones including estrogens have long been implicated in the course of melanoma, but the conclusion is controversial. Estrogen receptors (ERs) and insulin-like growth factor 1 receptor (IGF1R) show extensive...

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Bibliographic Details
Main Authors: Tze-An Yuan, Vandy Yourk, Ali Farhat, Katherine L. Guo, Angela Garcia, Frank L. Meyskens, Feng Liu-Smith
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
cutaneous melanoma
gender disparities
estrogen receptors
insulin-like growth factor 1
insulin-like growth factor 1 receptor
genetic variants
Online Access:https://www.mdpi.com/1422-0067/21/5/1776

Internet

https://www.mdpi.com/1422-0067/21/5/1776

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