Evaluation of Radioiodinated Fluoronicotinamide/Fluoropicolinamide-Benzamide Derivatives as Theranostic Agents for Melanoma

Evaluation of Radioiodinated Fluoronicotinamide/Fluoropicolinamide-Benzamide Derivatives as Theranostic Agents for Melanoma

Malignant melanoma is the most harmful type of skin cancer and its incidence has increased in this past decade. Early diagnosis and treatment are urgently desired. In this study, we conjugated picolinamide/nicotinamide with the pharmacophore of <sup>131</sup>I-MIP-1145 to develop <sup...

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Bibliographic Details
Main Authors: Chao-Cheng Chen, Yang-Yi Chen, Yi-Hsuan Lo, Ming-Hsien Lin, Chih-Hsien Chang, Chuan-Lin Chen, Hsin-Ell Wang, Chun-Yi Wu
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
melanoma
<sup>131</sup>I-iodofluoropicolinamide benzamide (<sup>131</sup>I-IFPABZA)
<sup>131</sup>I-iodofluoronicotiamide benzamide (<sup>131</sup>I-IFNABZA)
theranostic agent
Online Access:https://www.mdpi.com/1422-0067/21/18/6597

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https://www.mdpi.com/1422-0067/21/18/6597

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