Comparison of an ordinal endpoint to time-to-event, longitudinal, and binary endpoints for use in evaluating treatments for severe influenza requiring hospitalization

Background/aims: The Food and Drug Administration recommends research into developing well-defined and reliable endpoints to evaluate treatments for severe influenza requiring hospitalization. A novel 6-category ordinal endpoint of patient health status after 7 days that ranges from death to hospita...

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Bibliographic Details
Main Authors: Ross L. Peterson, David M. Vock, Abdel Babiker, John H. Powers, III, Sally Hunsberger, Brian Angus, Armando Paez, James D. Neaton
Format: Article
Language:English
Published: Elsevier 2019-09-01
Series:Contemporary Clinical Trials Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2451865419300201