MOLECULAR AND CELLULAR CHANGES IN ARTERIAL FUNCTION OVER THE LIFE COURSE – FROM ACCELERATED AGEING TO CALCIFICATION
Vascular stiffening and calcification are hallmarks of ageing and these pathologies are accelerated in patients with diabetes and renal failure. Emerging evidence has defined a role for nuclear lamina defects and the DNA damage response in driving vascular calcification. The mechanisms responsible a...
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| Format: | Article |
| Language: | English |
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Atlantis Press
2018-12-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125929980/view |