T Cell Dysfunction and Exhaustion in Cancer

Tumor immunotherapy is a promising therapeutic strategy for patients with advanced cancers. T cells are key mediators of antitumor function that specifically recognize and react to tumor-expressing antigens and have proven critical for cancer immunotherapy. However, T cells are not as effective agai...

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Bibliographic Details
Main Authors: Zhen Zhang, Shasha Liu, Bin Zhang, Liang Qiao, Yi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00017/full