Influence of Normal Aging on Brain Autophagy: A Complex Scenario

Misfolded proteins are pathological findings in some chronic neurodegenerative disorders including Alzheimer’s, Parkinson’s, and Huntington’s diseases. Aging is a major risk factor for these disorders, suggesting that the mechanisms responsible for clearing misfolded proteins from the brain, the ubi...

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Bibliographic Details
Main Author: David A. Loeffler
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00049/full