A Chimeric Analysis of the Opioid Receptor Domains Critical for the Binding Selectivity of μ Opioid Ligands

The μ opioid receptor plays a key role in mediating the physiological, pharmacological, and behavioral effects of endogenous opioids and of opiate drugs such as morphine and heroin. This study examines the structural features critical to the selective binding of μ ligands to the μ receptor as oppose...

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Bibliographic Details
Main Authors: Brendon Watson, Fan Meng, Huda Akil
Format: Article
Language:English
Published: Elsevier 1996-02-01
Series:Neurobiology of Disease
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996196900091