EZH1/2 Inhibitors Favor ILC3 Development from Human HSPC-CD34<sup>+</sup> Cells

The dysregulation of epigenetic modifications has a well-established role in the development and progression of hematological malignancies and of solid tumors. In this context, EZH1/2 inhibitors have been designed to interfere with EZH1/2 enzymes involved in histone methylation (e.g., H3K27me3), lea...

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Bibliographic Details
Main Authors: Laura Damele, Adriana Amaro, Alberto Serio, Silvia Luchetti, Ulrich Pfeffer, Maria Cristina Mingari, Chiara Vitale
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/2/319