Synthesis, Characterization and Activity Evaluation of Matrinic Acid Derivatives as Potential Antiproliferative Agents

A series of new matrinic acid derivatives 5a–e was synthesized. The chemical structures of the synthesized compounds were confirmed by 1H-NMR, 13C-NMR, and electrospray ionization mass spectroscopy. The anti-tumor activities were also investigated in vitro by evaluating the effect of synthesized com...

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Bibliographic Details
Main Authors: Jian-Jun Liu, Qin Tu, Rui Liu, Dong-En Wang, Fan Chao, Jinyi Wang
Format: Article
Language:English
Published: MDPI AG 2013-05-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/5/5420