Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Bacterial coinfection restrains antiviral CD8 T-cell response via LPS-induced inhibitory NK cells

Exposure to multiple pathogens is common in nature, yet interactions between the immune components targeting bacterial and viral pathogens during co-infection are poorly understood. Here the authors show that bacteria-derived LPS induces cytotoxic NK cells that suppress antiviral CD8 T cell response...

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Bibliographic Details
Main Authors: Tobias Straub, Marina A. Freudenberg, Ulrike Schleicher, Christian Bogdan, Georg Gasteiger, Hanspeter Pircher
Format: Article
Language:English
Published: Nature Publishing Group 2018-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06609-z

Internet

https://doi.org/10.1038/s41467-018-06609-z

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