Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer

Tissue Effects in a Randomized Controlled Trial of Short-term Finasteride in Early Prostate Cancer

Background: In the Prostate Cancer Prevention Trial, finasteride selectively suppressed low-grade prostate cancer and significantly reduced the incidence of prostate cancer in men treated with finasteride compared with placebo. However, an apparent increase in high-grade disease was also observed am...

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Bibliographic Details
Main Authors: Jeri Kim, John W. Davis, Eric A. Klein, Cristina Magi-Galluzzi, Yair Lotan, John F. Ward, Louis L. Pisters, Joseph W. Basler, Curtis A. Pettaway, Andrew Stephenson, Elsa M. Li Ning Tapia, Eleni Efstathiou, Xuemei Wang, Kim-Anh Do, J. Jack Lee, Ivan P. Gorlov, Lana A. Vornik, Ashraful M. Hoque, Ina N. Prokhorova, Howard L. Parnes, Scott M. Lippman, Ian M. Thompson, Powel H. Brown, Christopher J. Logothetis, Patricia Troncoso
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:EBioMedicine
Subjects:
Prostate cancer
5α-reductase inhibitors
Finasteride
Cancer prevention
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416301347

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http://www.sciencedirect.com/science/article/pii/S2352396416301347

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