Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester.

Non-Invasive Microbial Metabolic Activity Sensing at Single Cell Level by Perfusion of Calcein Acetoxymethyl Ester.

Phase contrast microscopy cannot give sufficient information on bacterial metabolic activity, or if a cell is dead, it has the fate to die or it is in a viable but non-growing state. Thus, a reliable sensing of the metabolic activity helps to distinguish different categories of viability. We present...

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Bibliographic Details
Main Authors: Christina E M Krämer, Abhijeet Singh, Stefan Helfrich, Alexander Grünberger, Wolfgang Wiechert, Katharina Nöh, Dietrich Kohlheyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4625966?pdf=render

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http://europepmc.org/articles/PMC4625966?pdf=render

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