Generation of Glioblastoma Patient-Derived Intracranial Xenografts for Preclinical Studies

Glioblastoma multiforme (GBM) is the most malignant primary brain cancer affecting adults. Therapeutic options for GBM have remained the same for over a decade with no significant improvement. Many therapies that are successful in culture have failed in patients, likely due to the complex microenvir...

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Bibliographic Details
Main Authors: Amber E. Kerstetter-Fogle, Peggy L. R. Harris, Susann M. Brady-Kalnay, Andrew E. Sloan
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:International Journal of Molecular Sciences
Subjects:
GBM
Online Access:https://www.mdpi.com/1422-0067/21/14/5113