HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy.

HIV-1 residual viremia correlates with persistent T-cell activation in poor immunological responders to combination antiretroviral therapy.

BACKGROUND:The clinical significance and cellular sources of residual human immunodeficiency virus type 1 (HIV-1) production despite suppressive combination antiretroviral therapy (cART) remain unclear and the effect of low-level viremia on T-cell homeostasis is still debated. METHODOLOGY/PRINCIPAL...

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Bibliographic Details
Main Authors: Maud Mavigner, Pierre Delobel, Michelle Cazabat, Martine Dubois, Fatima-Ezzahra L'faqihi-Olive, Stéphanie Raymond, Christophe Pasquier, Bruno Marchou, Patrice Massip, Jacques Izopet
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2765414?pdf=render

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http://europepmc.org/articles/PMC2765414?pdf=render

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