Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation

Drosophila neuroblasts as a new model for the study of stem cell self-renewal and tumour formation

Drosophila larval brain stem cells (neuroblasts) have emerged as an important model for the study of stem cell asymmetric division and the mechanisms underlying the transformation of neural stem cells into tumour-forming cancer stem cells. Each Drosophila neuroblast divides asymmetrically to produc...

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Bibliographic Details
Main Authors: Song Li, Hongyan Wang, Casper Groth
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2014-07-01
Series:Bioscience Reports
Subjects:
asymmetric division
differentiation
neural stem cell
neuroblast
Notch
self-renewal
tumour formation
Online Access:http://www.bioscirep.org/bsr/034/e125/bsr034e125.htm

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http://www.bioscirep.org/bsr/034/e125/bsr034e125.htm

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