Estrogen mediates sex differences in preoptic neuropeptide and pituitary hormone production in medaka

Junpei Yamashita et al. use a medaka model to evaluate how neurons in the preoptic area that express the neuropeptides, PACAP and VIP, regulate pituitary hormones. Their results suggest that estrogen helps maintain sex-dependent activity of these neurons, leading to sexually dimorphic pituitary horm...

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Bibliographic Details
Main Authors: Junpei Yamashita, Yuji Nishiike, Thomas Fleming, Daichi Kayo, Kataaki Okubo
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02476-5