Clinical implications of recurrent gene mutations in acute myeloid leukemia

Clinical implications of recurrent gene mutations in acute myeloid leukemia

Abstract Acute myeloid leukemia (AML) is a genetically heterogeneous clonal malignancy characterized by recurrent gene mutations. Genomic heterogeneity, patients’ individual variability, and recurrent gene mutations are the major obstacles among many factors that impact treatment efficacy of the AML...

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Bibliographic Details
Main Authors: Jifeng Yu, Yingmei Li, Danfeng Zhang, Dingming Wan, Zhongxing Jiang
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Experimental Hematology & Oncology
Subjects:
Recurrent gene mutation
Acute myeloid leukemia (AML)
FLT3
CEBPA
NPM1
RUNX1
Online Access:http://link.springer.com/article/10.1186/s40164-020-00161-7

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http://link.springer.com/article/10.1186/s40164-020-00161-7

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