P95 EFFECT OF CHRONIC INFLAMMATION INHIBITION WITH SALSALATE ON AORTIC STIFFNESS AND VASCULAR ENDOTHELIAL FUNCTION IN OLDER ADULTS: A RANDOMIZED CONTROLLED STUDY
Chronic activation of the proinflammatory transcription factor nuclear factor kappa-B (NFkB) is linked to age-associated vascular dysfunction. Acute inhibition of NFkB with high-dose salsalate (>4g), a non-acetylated salicylate known to block NFkB activation, improves aortic stiffness and end...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Atlantis Press
2017-12-01
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| Series: | Artery Research |
| Online Access: | https://www.atlantis-press.com/article/125930304/view |