IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions

Cytokines of the IL-12 family show structural similarities but have distinct functions in the immune system. Prominent members of this cytokine family are the pro-inflammatory cytokines IL-12 and IL-23. These two cytokines share cytokine subunits and receptor chains but have different functions in a...

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Bibliographic Details
Main Authors: Doreen M. Floss, Jens M. Moll, Jürgen Scheller
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/10/2184