DrImpute: imputing dropout events in single cell RNA sequencing data

DrImpute: imputing dropout events in single cell RNA sequencing data

Abstract Background The single cell RNA sequencing (scRNA-seq) technique begin a new era by allowing the observation of gene expression at the single cell level. However, there is also a large amount of technical and biological noise. Because of the low number of RNA transcriptomes and the stochasti...

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Bibliographic Details
Main Authors: Wuming Gong, Il-Youp Kwak, Pruthvi Pota, Naoko Koyano-Nakagawa, Daniel J. Garry
Format: Article
Language:English
Published: BMC 2018-06-01
Series:BMC Bioinformatics
Subjects:
Single cell RNA sequencing data
Dropout events
Imputation
Next generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12859-018-2226-y

Internet

http://link.springer.com/article/10.1186/s12859-018-2226-y

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