TGF-β Regulates Hepatocellular Carcinoma Progression by Inducing Treg Cell Polarization

Background/Aims: TGF-β plays a key role in the progression of various tumors. The main objective of our study was to investigate whether TGF-β is able to regulate N-nitrosodiethylamine (DEN)-induced hepatocellular carcinoma (HCC) progression in a mouse model by inducing Treg cell polarization. Metho...

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Bibliographic Details
Main Authors: Yinan Shen, Yongpeng Wei, Zhouchong Wang, Yingying Jing, Haiguan He, Jianyong Yuan, Rong Li, Qiudong Zhao, Lixin Wei, Tian Yang, Junhua Lu
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
HCC
Online Access:http://www.karger.com/Article/FullText/373976