Immune Complexes of Beta-2-Glycoprotein I and IgA Antiphospholipid Antibodies Identify Patients With Elevated Risk of Thrombosis and Early Mortality After Heart Transplantation

Immune Complexes of Beta-2-Glycoprotein I and IgA Antiphospholipid Antibodies Identify Patients With Elevated Risk of Thrombosis and Early Mortality After Heart Transplantation

Background: The presence of anti-Beta 2 glycoprotein antibodies (aB2GP1) of IgA isotype is common in patients with functional impairment of the organs in which B2GP1 is elaborated. Pretransplant IgA aB2GP1 has been associated with increased risk of thrombosis in kidney and heart transplanted patient...

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Bibliographic Details
Main Authors: Manuel Serrano, Laura Morán, Jose Angel Martinez-Flores, Esther Mancebo, Daniel Pleguezuelo, Oscar Cabrera-Marante, Juan Delgado, Antonio Serrano
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Immunology
Subjects:
antiphospholipid
heart transplant
circulating immune-complexes
anti-beta-2-glycoprotein I
non-criteria aPL
IgA
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02891/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02891/full

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