IRE1α Signaling Pathways Involved in Mammalian Cell Fate Determination

A diverse array of cellular stresses can lead to accumulation of misfolded or unfolded proteins in endoplasmic reticulum (ER), which subsequently elicits ER stress. Inositol-requiring enzyme 1α (IRE1α) is the most sensitive of the three unfolded protein response (UPR) branches which are triggered to...

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Bibliographic Details
Main Authors: Jie Wu, Guang-Ting He, Wei-Jin Zhang, Jing Xu, Qiao-Bing Huang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2016-02-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/443039