Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality

Immunohistological and Ultrastructural Study of the Inflammatory Response to Perforated Polyimide Cortical Implants: Mechanisms Underlying Deterioration of Electrophysiological Recording Quality

The deterioration of field potential (FP) recording quality and yield by in vivo multielectrode arrays (MEA) within days to weeks of implantation severely limits progress in basic and applied brain research. The prevailing hypothesis is that implantation of MEA platforms initiate and perpetuate infl...

Full description

Bibliographic Details
Main Authors: Shun-Ho Huang, Nava Shmoel, Maciej M. Jankowski, Hadas Erez, Aviv Sharon, Wesal Abu-Salah, Israel Nelken, Aryeh Weiss, Micha E. Spira
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Neuroscience
Subjects:
neural interface
foreign body response
polyimide
field potentials recordings
immunohistology
ultrastructure
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00926/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00926/full

Similar Items