MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

The neurological changes in children living with perinatal HIV (PHIV) on antiretroviral therapy (ART) can be studied at a metabolic level through proton magnetic resonance spectroscopy. While previous studies in children have largely focused on individual metabolite changes, investigating patterns w...

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Bibliographic Details
Main Authors: Amy S. Graham, Martha J. Holmes, Francesca Little, Els Dobbels, Mark F. Cotton, Barbara Laughton, Andre van der Kouwe, Ernesta M. Meintjes, Frances C. Robertson
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
Antiretroviral therapy
Basal ganglia
HIV
Midfrontal gray matter
Peritrigonal white matter
Proton magnetic resonance spectroscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303429

Internet

http://www.sciencedirect.com/science/article/pii/S2213158220303429

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