Cysteamine Inhibits Glycine Utilisation and Disrupts Virulence in Pseudomonas aeruginosa

Cysteamine Inhibits Glycine Utilisation and Disrupts Virulence in Pseudomonas aeruginosa

Pseudomonas aeruginosa is a major opportunistic human pathogen which employs a myriad of virulence factors. In people with cystic fibrosis (CF) P. aeruginosa frequently colonises the lungs and becomes a chronic infection that evolves to become less virulent over time, but often adapts to favour pers...

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Bibliographic Details
Main Authors: Douglas J. Fraser-Pitt, Stephen K. Dolan, David Toledo-Aparicio, Jessica G. Hunt, Daniel W. Smith, Niamh Lacy-Roberts, Piumi Sara Nupe Hewage, Teodora N. Stoyanova, Erin Manson, Kevin McClean, Neil F. Inglis, Derry K. Mercer, Deborah A. O’Neil
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
virulence
biofilm
Pseudomonas aeruginosa
novel therapeutic
glycine cleavage complex
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2021.718213/full

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https://www.frontiersin.org/articles/10.3389/fcimb.2021.718213/full

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