Detecting overlapping protein complexes by rough-fuzzy clustering in protein-protein interaction networks.

In this paper, we present a novel rough-fuzzy clustering (RFC) method to detect overlapping protein complexes in protein-protein interaction (PPI) networks. RFC focuses on fuzzy relation model rather than graph model by integrating fuzzy sets and rough sets, employs the upper and lower approximation...

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Bibliographic Details
Main Authors: Hao Wu, Lin Gao, Jihua Dong, Xiaofei Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3958373?pdf=render