Effects of Fluoxetine on Hippocampal Neurogenesis and Neuroprotection in the Model of Global Cerebral Ischemia in Rats

Effects of Fluoxetine on Hippocampal Neurogenesis and Neuroprotection in the Model of Global Cerebral Ischemia in Rats

A selective serotonin reuptake inhibitor, fluoxetine, has recently attracted a significant interest as a neuroprotective therapeutic agent. There is substantial evidence of improved neurogenesis under fluoxetine treatment of brain ischemia in animal stroke models. We studied long-term effects of flu...

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Bibliographic Details
Main Authors: Marina Khodanovich, Alena Kisel, Marina Kudabaeva, Galina Chernysheva, Vera Smolyakova, Elena Krutenkova, Irina Wasserlauf, Mark Plotnikov, Vasily Yarnykh
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
global brain ischemia
neurogenesis
fluoxetine
hippocampus
dentate gyrus
inflammation
CA1
antidepressants
neural stem cells
rats
Online Access:http://www.mdpi.com/1422-0067/19/1/162

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http://www.mdpi.com/1422-0067/19/1/162

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