SDF-1α Reduces Human Natural Killer Cell Cytotoxicity against Chronic Myelogenous Leukemia K562 Cells

Stromal cell-derived factor-1 alpha (SDF-1α) has been shown to be up-regulated in a variety of malignancies. So that, its expression is associated with poor prognosis and invasiveness. Natural killer (NK) cells are important effector cells against virus-infected and transformed cells. Especially th...

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Bibliographic Details
Main Authors: Alireza Mardomi, Hadi Hossein-Nataj, Narjes Jafari, Nabiallah Mohammadi, Saeid Abediankenari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2019-10-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Subjects:
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2265