Oxidative damage to urinary proteins from the GRMD dog and mdx mouse as biomarkers of dystropathology in Duchenne muscular dystrophy.

Oxidative damage to urinary proteins from the GRMD dog and mdx mouse as biomarkers of dystropathology in Duchenne muscular dystrophy.

Duchenne muscular dystrophy (DMD) is a lethal, X-chromosome linked muscle-wasting disease affecting about 1 in 3500-6000 boys worldwide. Myofibre necrosis and subsequent loss of muscle mass are due to several molecular sequelae, such as inflammation and oxidative stress. We have recently shown incre...

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Bibliographic Details
Main Authors: Jessica R Terrill, Basma A Al-Mshhdani, Marisa N Duong, Catherine D Wingate, Zahra Abbas, Angelo P Baustista, Amanda K Bettis, Cynthia J Balog-Alvarez, Joe N Kornegay, Peter P Nghiem, Miranda D Grounds, Peter G Arthur
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0240317

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