Overexpression of GRP78/BiP in P-Glycoprotein-Positive L1210 Cells is Responsible for Altered Response of Cells to Tunicamycin as a Stressor of the Endoplasmic Reticulum

P-glycoprotein (P-gp, ABCB1 member of the ABC (ATP-binding cassette) transporter family) localized in leukemia cell plasma membranes is known to reduce cell sensitivity to a large but well-defined group of chemicals known as P-gp substrates. However, we found previously that P-gp-positive sublines o...

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Bibliographic Details
Main Authors: Mário Šereš, Lucia Pavlíková, Viera Boháčová, Tomáš Kyca, Ivana Borovská, Boris Lakatoš, Albert Breier, Zdena Sulová
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/4/890