Estimating heritability of complex traits from genome-wide association studies using IBS-based Haseman-Elston regression

Exploring heritability of complex traits is a central focus of statistical genetics. Among various previously proposed methods to estimate heritability, variance component methods are advantageous when estimating heritability using markers. Due to the high-dimensional nature of data obtained from ge...

Full description

Bibliographic Details
Main Author: Guo-Bo eChen
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00107/full