Delineating Human B Cell Precursor Development With Genetically Identified PID Cases as a Model

Delineating Human B Cell Precursor Development With Genetically Identified PID Cases as a Model

B-cell precursors (BCP) arise from hematopoietic stem cells in bone marrow (BM). Identification and characterization of the different BCP subsets has contributed to the understanding of normal B-cell development. BCP first rearrange their immunoglobulin (Ig) heavy chain (IGH) genes to form the pre-B...

Full description

Bibliographic Details
Main Authors: Marjolein W. J. Wentink, Tomas Kalina, Martin Perez-Andres, Lucia del Pino Molina, Hanna IJspeert, François G. Kavelaars, Arjan C. Lankester, Quentin Lecrevisse, Jacques J. M. van Dongen, Alberto Orfao, Mirjam van der Burg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
next generation sequence (NGS)
immunoglobulin repertoire
bone marrow
flow cytometry
precursor B-cell
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02680/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02680/full

Similar Items