ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

ANGPTL8 promotes the ability of ANGPTL3 to bind and inhibit lipoprotein lipase

Objective: Several members of the angiopoietin-like (ANGPTL) family of proteins, including ANGPTL3 and ANGPTL8, regulate lipoprotein lipase (LPL) activity. Deficiency in either ANGPTL3 or ANGPTL8 reduces plasma triglyceride levels and increases LPL activity, whereas overexpression of either protein...

Full description

Bibliographic Details
Main Authors: Xun Chi, Emily C. Britt, Hannah W. Shows, Alexander J. Hjelmaas, Shwetha K. Shetty, Emily M. Cushing, Wendy Li, Alex Dou, Ren Zhang, Brandon S.J. Davies
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Molecular Metabolism
Subjects:
Plasma triglycerides
Lipoprotein metabolism
Lipolysis
Lipase inhibition
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817303307

Internet

http://www.sciencedirect.com/science/article/pii/S2212877817303307

Similar Items