Recombinant baculovirus associated with bilosomes as an oral vaccine candidate against HEV71 infection in mice.

BACKGROUND: Human enterovirus 71 (HEV71) is one of the major pathogen responsible for hand, foot and mouth disease (HFMD). Currently no effective vaccine or antiviral drugs are available. Like poliovirus, EV71 is transmitted mainly by the feco-oral route. To date the majority of the studied EV71 vac...

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Bibliographic Details
Main Authors: Balraj Premanand, Mookkan Prabakaran, Tanja K Kiener, Jimmy Kwang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3563597?pdf=render