Maintenance of cell type-specific connectivity and circuit function requires Tao kinase

It is unclear how circuit specificity and function are maintained during organismal growth. In this study, authors show that connectivity between primary nociceptors and their downstream neurons scales with animal size and that Ste20-like kinase Tao acts as a negative regulator of synaptic growth re...

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Bibliographic Details
Main Authors: Federico Marcello Tenedini, Maria Sáez González, Chun Hu, Lisa Hedegaard Pedersen, Mabel Matamala Petruzzi, Bettina Spitzweck, Denan Wang, Melanie Richter, Meike Petersen, Emanuela Szpotowicz, Michaela Schweizer, Stephan J. Sigrist, Froylan Calderon de Anda, Peter Soba
Format: Article
Language:English
Published: Nature Publishing Group 2019-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-11408-1