Enhanced neutralizing antibody titers and Th1 polarization from a novel Escherichia coli derived pandemic influenza vaccine.

Influenza pandemics can spread quickly and cost millions of lives; the 2009 H1N1 pandemic highlighted the shortfall in the current vaccine strategy and the need for an improved global response in terms of shortening the time required to manufacture the vaccine and increasing production capacity. Her...

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Bibliographic Details
Main Authors: David A G Skibinski, Brendon J Hanson, Yufang Lin, Veronika von Messling, Andrea Jegerlehner, Jason Boon Sern Tee, De Hoe Chye, Steven K K Wong, Amanda A P Ng, Hui Yin Lee, Bijin Au, Bernett T K Lee, Lucia Santoso, Michael Poidinger, Anna-Marie Fairhurst, Alex Matter, Martin F Bachmann, Philippe Saudan, John E Connolly
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3799843?pdf=render