Humoral immune responses to a single allele PfAMA1 vaccine in healthy malaria-naïve adults.

Plasmodium falciparum: apical membrane antigen 1 (AMA1) is a candidate malaria vaccine antigen expressed on merozoites and sporozoites. The polymorphic nature of AMA1 may compromise vaccine induced protection. The humoral response induced by two dosages (10 and 50 µg) of a single allele AMA1 antigen...

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Bibliographic Details
Main Authors: Edmond J Remarque, Meta Roestenberg, Sumera Younis, Vanessa Walraven, Nicole van der Werff, Bart W Faber, Odile Leroy, Robert Sauerwein, Clemens H M Kocken, Alan W Thomas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3387192?pdf=render